News The best couples of Grey's Anatomy vote for your favorite couple TOP 14: Alex / Ava TOP 13: George / Callie TOP 12: Addison / Alex TOP 11: Adddison / Derek TOP 10: George / Izzie TOP 9: Erica / Callie TOP 8: Alex / Lexie TOP 7: Lexie / George TOP 6: Addison7Mark TOP 5: Cristina / Preston TOP 4: Izzie / Denny TOP 3: Kevin / Christina TOP 2: Alex / Iizzie TOP 1: Derek / Meredith